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pentobarbital will reduce the level or influence of gefitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lower the level or influence of glecaprevir/pibrentasvir by affecting hepatic/intestinal enzyme CYP3A4 metabolism.pentobarbital will lessen the extent or result of tofacitinib by impacting hepatic/intestinal enzy